Cancer Diagnostic Methods Evaluated Using Hettich ROTINA 380 Benchtop Centrifuge
The Hettich ROTINA 380 benchtop centrifuge was cited in a pilot study entitled "Liquid Based vs. Conventional Cytology for Evaluation of Fine Needle Aspiration Biopsies Obtained by Pulmonary Physicians."
In the study, researchers sought to compare the diagnostic yield of liquid based cytology (LBC) with conventional cytology methods in the evaluation of intrathoracic mass lesions.
Transthoracic fine needle aspiration (TTFNA) was performed on 30 consecutive patients. Aspirates from three different locations were taken and expressed on to glass slides. A fourth was taken and washed into a vial containing BD CytoRich™ for LBC testing. During the ensuing procedures, the Hettich ROTINA 380 was used in the BD Diagnostic systems to centrifuge the specimens.
Ultimately, “conventional cytology onsite yielded a diagnosis in 26 patients (86.7%), whereas LBC was diagnostic in 11 patients (36.7% p<0.001).” LBC was only able to diagnose cases of epithelial carcinomas. Though the LBC method performed well under the diagnostic yield of conventional cytology, the authors of the study noted “the total volume of material aspirated for the LBC method was not equal to that aspirated for routine cytology.” The study suggests additional randomized studies with equal volumes for both methods for a more clear determination of the efficacy of LBC.
Hettich’s comprehensive line of centrifuges enables scientists to conduct important testing and research, such as this study on new methods for evaluating fine needle aspiration biopsies. The Hettich ROTINA 380 is a high-capacity, general-purpose benchtop centrifuge suited for routine and specialized laboratory applications.
Learn more about the Hettich ROTINA 380 benchtop centrifuge at: www.hettweb.com/hettich-rotina-380-centrifuge.html